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The main idea behind DSPy is that you can’t modify the weights, but you can perhaps modify the prompts. DSPy’s original primary customer was multi-llm-agent systems where you have a chain / graph of LLM calls (perhaps mostly or all to OpenAI GPT) and you have some metric (perhaps vague) that you want to increase. While the idea may seem a bit weird, there have been various success stories, such as a UoT team winning medical-notes-oriented competition using DSPy https://arxiv.org/html/2404.14544v1


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