According to the Arch Wiki, the Linux side is "fairly mature"[0]. The Mesa3D documentation leaves a similar impression regarding OpenGL[1], mentioning that the Linux drivers, including the ones for 3D support, are mainline since 4.4 (released in 2016[2]) with Qemu support since version 2.5 (released around 2015[2]), so I guess, the assessment from the Arch Wiki sounds about right.
The Venus driver for Vulkan is described as "experimental" [4], with Linux kernel side support merged in version 5.16 (release in early 2022[5]).
RedHat is developing VirtIO drivers for Windows[6], but apparently they gave up the work on the OpenGL ICD driver in favor of Vulkan[7]?
That said, I have no clue what the situation on various BSDs looks like. I guess on OpenBSD, this is a first step towards making this
chain work?