The same building used to be the headquarters of Sega of America back during their heyday. (the level design of Sonic Adventure 2 was heavily influenced by San Francisco / Bay Area)
Not CNet, ZDNet (Ziff-Davis) and TechTV (Which started life as ZDTV). Worked there can attest ;-)
A lot of the Adobe Stuff including the Macromedia divisions when they were alive are still immediately next door or across the street. I think their use of 650 Townsend was mostly for overflow office space.
